Norie Araki Selected Research

GTPase-Activating Proteins (GTPase-Activating Protein)

9/2014	Translationally controlled tumor protein is a novel biological target for neurofibromatosis type 1-associated tumors.
11/2005	The neurofibromatosis type 1 gene product neurofibromin enhances cell motility by regulating actin filament dynamics via the Rho-ROCK-LIMK2-cofilin pathway.
1/2004	PKA phosphorylation and 14-3-3 interaction regulate the function of neurofibromatosis type I tumor suppressor, neurofibromin.
7/2003	Neurofibromatosis type I tumor suppressor neurofibromin regulates neuronal differentiation via its GTPase-activating protein function toward Ras.

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Norie Araki Research Topics

Disease

19	Neoplasms (Cancer) 01/2022 - 10/2002
12	Cholangiocarcinoma 01/2022 - 01/2007
6	Neurofibromatosis 1 (Neurofibromatosis Type I) 05/2013 - 03/2003
3	Glioma (Gliomas) 01/2022 - 01/2013
2	Neoplasm Metastasis (Metastasis) 01/2022 - 03/2008
1	Lymphatic Metastasis 01/2022
1	Carcinogenesis 01/2020
1	Obesity 01/2020
1	Esophageal Squamous Cell Carcinoma 11/2018
1	Necrosis 07/2018
1	Stomach Neoplasms (Stomach Cancer) 03/2016
1	Neurofibrosarcoma (MPNST) 09/2014
1	Neurofibromatoses (Neurofibromatosis) 09/2014
1	Wounds and Injuries (Trauma) 04/2013
1	Glioblastoma (Glioblastoma Multiforme) 01/2013
1	Inflammation (Inflammations) 05/2011
1	Genetic Translocation (Chromosomal Translocation) 01/2010
1	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2010
1	Hemolysis 10/2009
1	Pheochromocytoma 10/2009
1	Pancreatitis 08/2006
1	Warts (Wart) 10/2002
1	Nervous System Diseases (Neurological Disorders) 09/2002
1	Hashimoto's encephalitis 09/2002
1	Central Nervous System Diseases (CNS Diseases) 09/2002

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 01/2022 - 07/2003
5	Neurofibromin 1 (Neurofibromin)IBA 05/2013 - 07/2003
4	Polysaccharides (Glycans)IBA 01/2022 - 02/2018
4	GTPase-Activating Proteins (GTPase-Activating Protein)IBA 09/2014 - 07/2003
3	Biomarkers (Surrogate Marker)IBA 01/2022 - 09/2014
3	Biological ProductsIBA 01/2019 - 03/2008
3	ArtesunateIBA 01/2019 - 09/2014
3	ras GTPase-Activating Proteins (ras-GAP)IBA 05/2013 - 07/2003
3	Pharmaceutical PreparationsIBA 01/2013 - 01/2007
2	LectinsIBA 01/2022 - 01/2020
2	Messenger RNA (mRNA)IBA 01/2022 - 09/2014
2	EnzymesIBA 01/2020 - 01/2007
2	Translationally-Controlled 1 Tumor ProteinIBA 01/2019 - 09/2014
2	VimentinIBA 05/2018 - 04/2013
2	IntegrinsIBA 03/2016 - 01/2013
2	CarbohydratesIBA 10/2013 - 08/2011
2	methionine aminopeptidase 2IBA 01/2012 - 01/2007
2	Galectin 3 (LGALS3)IBA 11/2009 - 03/2008
1	Apoptosis Inducing FactorIBA 01/2022
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2022
1	ForminsIBA 01/2022
1	ErbB Receptors (EGF Receptor)IBA 10/2021
1	TriterpenesIBA 10/2021
1	6-methyladenineIBA 01/2020
1	Vicia lectinsIBA 01/2020
1	Cyclin D1IBA 01/2020
1	ProteomeIBA 01/2019
1	Peptide Elongation Factors (Elongation Factor)IBA 01/2019
1	4- (4- dihexadecylaminostyryl)- N- methylpyridium (DiA)IBA 01/2019
1	Valine-tRNA LigaseIBA 01/2019
1	alpha-hydroxyglutarateIBA 11/2018
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 11/2018
1	L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA 07/2018
1	Caspase 3 (Caspase-3)IBA 07/2018
1	Chloroquine (Aralen)FDA LinkGeneric 07/2018
1	sophora japonica agglutininIBA 02/2018
1	AcetylgalactosamineIBA 02/2018
1	TOR Serine-Threonine KinasesIBA 09/2014
1	Sirolimus (Rapamycin)FDA Link 09/2014
1	S 27IBA 10/2013
1	EpitopesIBA 10/2013
1	Dyneins (Dynein)IBA 05/2013
1	matrigelIBA 04/2013
1	AnaphylatoxinsIBA 04/2013
1	Anaphylatoxin C5a ReceptorIBA 04/2013
1	Matrix Metalloproteinases (MMPs)IBA 04/2013
1	Cadherins (E-Cadherin)IBA 04/2013
1	DNA (Deoxyribonucleic Acid)IBA 01/2013
1	LigandsIBA 01/2013
1	Temozolomide (Temodar)FDA LinkGeneric 01/2013
1	Cyclophilin AIBA 01/2012
1	Methionine (L-Methionine)FDA Link 01/2012
1	fumagillinIBA 01/2012
1	Peptide Hydrolases (Proteases)FDA Link 01/2012
1	AntigensIBA 08/2011
1	Mucin 5ACIBA 08/2011
1	Chemokine ReceptorsIBA 05/2011
1	ChemokinesIBA 05/2011
1	Imatinib Mesylate (Gleevec)FDA Link 01/2010
1	bcr-abl Fusion ProteinsIBA 01/2010
1	CyclodextrinsIBA 10/2009
1	Nerve Growth Factor (NGF)IBA 10/2009
1	Galectins (Galectin)IBA 03/2008
1	Small Interfering RNA (siRNA)IBA 03/2008
1	Proteinase-Activated ReceptorsIBA 08/2006
1	Myelin P0 Protein (Myelin Protein Zero)IBA 03/2003
1	Cyclin BIBA 10/2002
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 10/2002
1	AutoantigensIBA 09/2002
1	Phosphopyruvate Hydratase (Enolase)IBA 09/2002

Therapy/Procedure

4	Therapeutics 10/2021 - 03/2008
1	Drug Therapy (Chemotherapy) 07/2018